Research
Methods for Optimizing the Effectiveness of Assisted Reproductive Technology Programs using Pre-Implantation Genetic Testing
These guidelines describe a study whose purpose was to analyze the feasibility of performing genetic screening of embryos (Next Generation Sequencing - NGS) as part of infertility treatment cycles, to determine the relationship or its absence between the stage of development of the embryo and its survival, as well as an indicator of the successful development of pregnancy with the previous genetic screening. Based on the results of a comprehensive study, the effect of genetic screening, vitrification, oocyte competence and clinical indicators of patients on embryo survival was established.
Methods for Assessing Human Embryos to Increase Reproductive Potential
The embryological stage of ART programs is one of the most important, since the assessment of the quality of oocytes, their fertilization and in vitro cultivation to the stage of preimplantation embryos largely determines its success. Morphological evaluation of embryos is the main method of embryo selection. Time-lapse microscopy is one of the modern methods of selecting a high-quality embryo for transfer. In the analysis of many retrospective and prospective studies, they emphasize the advantage and lack of differences compared to traditional morphological assessment of the quality of embryos Almost all publications devoted to time-lapse microscopy have focused on determining the timing of specific events of embryo division and then using this information to create algorithms that help to select embryo for transfer.
The Symbol of the Griffin in the Primitive-Religious Views of the People of Central Asia
In this research, authors focused on learning primitive-religious views of the population in the Central Asia. Authors found that griffin belonging to religious- mystical imaginations; cults and early religious views of ancient times in the territory of Uzbekistan have historically experienced very large stages of development. Their images have changed in different ways and have improved in terms of form and content. Griffin symbol is widespread not only in the territory of Uzbekistan. Moreover, art of the ancient world: architecture, painting, sculpture, applied art are spread out.
Expression of Symbols Related to Idea of Fetishism in the Territory of Uzbekistan
This article analyzes the representation of symbols related to the ideas of fetishism in the territory of Uzbekistan. It discusses the symbols and symbols of the ancient, pre-Islamic and post-Islamic religious beliefs of the ancient peoples and nations that historically existed in the territory of Uzbekistan. Examples from ancient sources are given in a new interpretation.
Quantitative Determination of Ethyl Methyl Hydroxypyridina Succinate in the Preparation Seroxidol and its Bioequivalence
Nowadays, the most common spread diseases are cerebral circulation disorders, including ischaemic stroke and its consequences, such as dyscirculatory encephalopathy, vegetative-vascular dystonia, neurotic and neurosis-like disorders, memory and attention disorders or mental impairment, and atherosclerosis of the cerebral vessels. Research on the need for new drugs for those neurological disorders in Uzbekistan has been done and successfully produced an injectable solution of Seroxidol. This drug is an inhibitor of free radical processes and a membrane protector with antihypoxic, stress-protective, nootropic, anticonvulsant and anxiolytic effects. Seroxidol increases the resistance to the effects of various damaging factors (shock, hypoxia and ischaemia, cerebral circulation disorders, alcohol intoxication and antipsychotic drugs with neuroleptics) and improves the functional state of the ischaemic myocardium. It effectively restores myocardial contractility in cases of reversible cardiac dysfunction. Seroxidol contains ethyl methyl hydroxypyridine succinate and sodium metabisulfite.
The Argumentation Theory in Kalam in Maverannahr and Usage of its Practice Techniques in Discussions on the Websites of Uzbekistan
The article is dedicated to the historical prerequisites for the formation of the theory of argumentation in the works of representatives of the Kalam schools in Maverannahr in the 9th – 13th centuries. It is especially important to study the legacy of the Maturidian and Asharian Kalam when it comes to solving modern issues of argumentation and verification and conducting a religious examination in Uzbekistan, which began a new stage in its history.
Evoked Potentials in the Prognosis of Surgical Treatment of Cerebellar Syndrome in Chiari Malformation Type 1
The scientific work presents the results of a neurophysiological examination of 63 patients with cerebellar symptoms in Chiari malformation of type I according to MRI data. All patients underwent a multimodal protocol including BAEP, SSEP and ENMG examination. Neurophysiological criteria of the cerebellar syndrome in type 1 Chiari malformation have been identified, which in a comparative analysis are the most informative in decision making regarding conservative or surgical treatment.
The Results of Hearing Screening at the Children ith Down Syndrome Andijan Region f Uzbekistan
This article presents the primary results of targeted hearing screening among children with Down syndrome, as one of the most common pathologies at risk of developing various forms of hearing loss. As a result of the screening according to the data of delayed otoacoustic emission and otoacoustic emission distortion product, out of the total number of children in 41.5 of cases, objective tests showed the presence of auditory dysfunction, i.e. the answer is refer. Thus, we found it expedient to carry out hearing screening in children with Down syndrome in order to prevent hearing loss, and secondary forms of delayed psychoverbal development associated with it.
Features of the Clinical Course of Urinary Stone Disease in the Farming Population
In the climatic conditions of the Fergana Valley of Uzbekistan, 2478 people aged 18-70 engaged in farming were studied in a one-time epidemiological study. Questionnaire, clinical, biochemical, instrumental and special urological examination methods were used. The clinical symptoms of urolithiasis are determined to have a number of specific features, including risk factors and comorbidity. Severe urolithiasis and exacerbation of symptoms are observed in patients with a risk factor of 12.8 times, and in the presence of comorbidity - up to 45.7%.
Current State of the National Education System of the Republic of Uzbekistan
The paper states that in recent years Uzbekistan has been making systematic efforts to improve the quality and effectiveness of the system of education and upbringing, the formation of modern knowledge and skills in kindergartens, pupils and students, ensuring mutual close cooperation and integration of the systems of education and science, the continuity and continuity of education. It is pointed out that the result of wide public discussion by the Presidential Decree was the adoption of the Development Strategy of New Uzbekistan for 2022- 2026 and the State Program for its implementation, a separate section of which includes a number of goals directly related to education, which is the subject of the article.
