Cetuximab, an anti-epidermal growth factor receptor (EGFR) antibody, has been widely used fortherapy of several kinds of malignant diseases. However, the anticancer effect is incomplete. The purpose of this study was to examine the synergism between the herbal drug, Polysaccharide K, and Cetuximab against gastrointestinal cancer cell lines in vitro and in vivo.Two gastrointestinal cancer cell lines positive for EGFR expression were used for this study. In the in vivo study, mice were xenografted with cancer cell lines subcutaneously. Neither PSK nor Cetuximab suppressed cell proliferation. However, when both drugs were administered, cancer growth was suppressed significantly compared with treatment with Cetuximab alone. This study demonstrated that PSK has the potential to enhance Cetuximab’s effect on gastrointestinal cancer.

Japan’s national identity tends to emphasize cultural values which often describe what Japan and its people are, and in some case, it suggests how they should behave accordingly. This paper analyzes the relations of identity, culture and tourism development in Japan. I argue that the promotion of Japan’s tourism is closely linked to the establishment of particular images of itself or how the Japanese see themselves, i.e., self-image. The Japanese government has paid attention to tourism development for the last few years amidst its declining economy. Japanese tourist developers and entrepreneurs have collectively been interested in constructing a Japanese brand, namely “Cool Japan” with emphasis on popular culture. I will examine Japan’s soft power through its growing interest in the development of pop cultural tourism. To build tourism all over Japan without delay, the popularity of modern Japanese culture becomes an effective marketing tool for local events, festivals, restaurants and other types of businesses. However, this is also to suggest that Japan’s overemphasis on popular culture could lead to the devaluation of the country’s tradition and history instead of economic prosperity.

The National Vaccination Programme (NVP) is an exceptionally effective intervention in the field of public health, aiming at eliminating mortality caused by diseases for which there are available vaccines. Background: The study aims at recording the factors that determine parents’ level of knowledge about vaccines and their attitudes in Greece. Methods: A total of 2995 parents were asked to fill in a specially structured questionnaire. The study was conducted in 107 Athens kindergartens. Results: 58.8% of the parents demonstrated a satisfactory level of knowledge and alertness with respect to vaccination and NVP. Parents’ age, educational level, professional status, nationality, religion and sources of information contribute to parental awareness over the importance of vaccination. Conclusions: Knowledge and timely information constitute the most important factors that positively affect the attitudes of parents with regard to vaccines and NVP. In-school education of parents may ensure their consistency in NVP implementation.

The weakest link in any security plan or implementation is a human. The weak links include everyone from the hourly paid end user to the owner of the company. Even many of today’s security professionals may not have the time or ability to perform their current duties and keep up with an ever-growing number of threats. If someone is not aware of a threat then they are going to behave as if there were none. The job of the security professional is to change this behavior. It involves using a combination of technology and education to help users understand and follow security requirements. Everyone needs to understand why we need to have security policies and why they need to be followed.

Most studies on soil characteristics have been centered on suitability for agricultural production and once a soil does not support crop production it is referred to as poor, unproductive, and finally abandoned. Such soil can be very useful for forest crop plantation. This study was designed to investigate characteristics and describe the forest soil in Ombi, southern Guinea savanna of Nigeria. Soil samples were collected randomly from three locations around the engineering department of Nasarawa State Polytechnic Lafia, at depth of 0-30cm. Samples (1kg each) were taken in plastics bags to the laboratory for studies. Physical and chemical properties were analyzed according to standard procedures. Results show that sand had the highest % in soil of the area (74.96). Bulk densities were within the same range (1.68; 1.77 and 1.78g/cm3) for sand, silt and clay respectively. Sand had the highest porosity (37.7%) while clay had the least (31.6%). Aggregate stability was least for sand (9.74%) and highest for clay (56.82%). Soil reaction was neutral (7.05); nitrogen and CEC were 1.6 and 12.3 Cmol kg -1 among others, while organic carbon was 4.82g/kg-1. The soil is described as light and falls under sandy loam. Forest plantation establishment will be worthwhile.

Prevalence of tobacco use is high among adults and youth in India, resulting in high mortality from diseases associated with it. Studies in different countries have established the consistency of the association between movie smoking and adolescent smoking. Besides having the largest population of adolescents in the world, India also is one of the major movies producing countries. Moreover a large number of Indian films have been found to display tobacco branding. Indian movies have large viewership not only in the country, but all over the world, making youth vulnerable to exposure to smoking scenes. The Indian anti tobacco law provides for ban on all forms of advertisements, promotion and sponsorship of tobacco products. The Indian Government tried to regulate smoking scenes in movies as per the provisions under the law way back in the year 2005. This was met with strong resistance by the film industry arguing inference in the freedom of expression by these provisions which were challenged in the court of law. Subsequent to support from the judiciary and positive rulings from the court of law, the Government went ahead and implemented regulation on scenes showing smoking and other tobacco use in movies and television programmes in October 2012. The law is under implementation For desirable and effective impact of the legislative provisions for regulating scenes depicting smoking and tobacco use in the movies, it is imperative to ensure that the motion pictures no longer serve as a source of tobacco promotion aimed at adolescents and youth.

This paper investigates covariates of neonatal and post-neonatal mortality in Bangladesh. The study uses the data extracted from the 2007 Bangladesh Demographic and Health Survey (BDHS). Multivariate proportional hazards models are employed to study the determinants of neonatal and post-neonatal mortality. The results show that father’s education, place of residence, housing materials, number of children under five years of age, and previous death of sibling have significant influence on neonatal mortality. The findings also indicate that mother’s education, toilet facility, number of children under five and breastfeeding have significant effect on post-neonatal mortality in Bangladesh.

The environmental conditions become more “civilized” during the time and implicit less favorable in general for the game. It came into sight some trace regarding the qualitative and also the quantitative regress of the products and subproducts from this domain. The analysis of the causal relations of the determinant factors and of the game population dynamic during the years showed that the actual situation is a consequence of some complex releasers factors (biotic and atrophic factors). We named the following from these factors: the environmental conditions of the game (climate, relief, temperature, humidity, the shelter, and the quit of this), the specie, the age, the gender of the game, the game fatten, the feed supplement, the stress before slaughter, the type of the used arms, electrocution of the game or other methods witch the game became unconsciously. Another category of factors refers to the treatment conditions after slaughter, respectively: the time to disembowel the game, the removal of the males’ testicles, the cooling and the correct manipulation during transportation of the game carcass, and the adequate storage of these carcasses for aging. In this paper we present some of these factors: age and gender which affect the game meat quality. In this paper we describe the influence of gender and the age on game meat quality. The results of the experiences showed that the male’s carcasses have higher contents in muscular and osseous tissue, comparative to the female’s carcasses. The female’s carcasses have higher contents in fat and conjunctive tissue, comparative to male’s carcasses. Also, these results point out that younger game have a soft meat, comparative to the adult game mea

Websites are the mean of exploring the information from the internet and have a significance role in the field of internet. Usability also plays an important role in the exploration of the websites. The objective of this paper is to highlight the usability issues in the Bangladesh universities websites and giving the suggestions about the usability of the websites regarding its fulfillment of the rules and provide an easy way for the user to use the website smoothly and with no time consumption. After checking of some parameters regarding the usability of the websites, it was concluded that some websites have the rules fulfillment gap due to which a user is not facilitated properly in exploration these sites. There is one university which completely follows the rules according to the mentioned parameters regarding the usability. It was concluded that all websites should be developed around the fixed rules and regulations and they should strictly follow these rules in facilitating the new and experienced users.

An experimental study was conducted to establish the influence of cylinder pressure on the combustion behavior of a pressurized kerosene cook stove. The test was carried out under ambient room conditions, by pressurizing and ignitingthe cook stove containing kerosene fuel at a maximum pressure of 1 bar. The combustion flame temperature, flameheight and structure and colour were arefully measured andrecorded from a pressure gauge mounted on the fuel tank, a thermocouple, vernier height meter and by direct flamephotography. The same process was repeated for vessel pressures of 0.8, 0.6, 0.4, 0.2, and 0 bar after an interval period of two minutes, and for B5, B10, B15, and B20 kerosene oil blends and B100 (i.e. 100%) diesel oil fuel samples respectively The experiment was replicated for each vessel pressure levels, adulterated fuel samples and their mean result values were analyzed. The results show that combustion temperature and flame height of tested fuel samples are strongly influenced by the vessel pressure, and at maximum pressure, the flame temperatures for B2, B10, B15, B20 fuel blends and diesel fuel are lower than the kerosene by 8.82%, 11.76%, 15.58%, 20.59% and 8.82%. While, the flame height for B5, B15, B20 fuel blends and diesel fuel are higher than the benchmark by 0.22%, 1.11%, 18.89% and 37.77%. The enhanced combustion quality of the predominating kerosene fuel samples is largely influenced by the calorific values, ignition ability, stoichiometric mixtures, rate of combustion reactions, concentrations of the reactants, fuelmass flow rate, and the specific heat capacity of the fuelsamples. The result of the statistical analysis show a strongregression and76.9% of the variation in vessel pressure couldbe accounted for by the control variables. Going by thepresent petroleum products pricing program in Nigeria, theillicit practice of kerosene –diesel fuel adulteration is notcapable of generating any economic benefit, and hence wouldassist to stem the tid