South Asian region is enjoying unprecedented booming economic growth. But this booming pecuniary emergence is becoming stifled by significant shortages in energy supply. If the exigent corrective steps are not initiated and implemented, it may be arduous to sustain the achieved growth rates and overall sustainable development. The region’s political leaders and its business community are recognizing gradually the need of cross-border energy exchange and promote regional energy trade. The region has available energy resources to produce power and it should be a matured option to interconnect the entire regional grid to mitigate the power crisis. This article identifies the potential and explicates the main opportunities of the south Asian region to cope up the energy crisis through sub continental power grid interconnection.