The effectiveness of ozone to remove the organic compound, chloropyrifos or cypermethrin from water at the two different levels of 1 and 2 ppm, for each and different contact times was studied. The recovered amounts of chloropyrifos or cypermethrin were extracted based on the solid phase extraction (SPE) method and then analyzed by GC-MS. The results demonstrated that the removal of these organic compounds by ozone increased with increasing the contact time. The removal percentages of chloropyrifos following ozone bubbling for different periods of 15, 30, 45 and 60 minutes at room temperature were 10.5, 96.3, 97.4 and 98.5% in case of samples fortified at the level of 1 ppm, while they were 79.6, 93.9, 94.7 and 96.1% at the level of 2 ppm, respectively. In case of cypermethrin, the removal percentages were 68.6, 90.5, 97 and 99.2% at 1 ppm level, whereas they found to be 30.5, 50, 84.7 and 92% at 2 ppm, respectively. Kinetic studies revealed that chloropyrifos and cypermethrin were found to be easily removed from water by ozone treatment.