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Clove (Eugenia Caryophyllata) Extraction and Synthesis of New Pyrazole Derivatives from Eugenol
S. Hamri, K. Rhazri, A. Hafid, H. Ouchetto, Y.Hajbi, M. Khouili
Volume 13 Issue 7
Global Journal of Science Frontier Researc
Volume 13 Issue 7
Global Journal of Science Frontier Researc
An efficient method for the preparation of novel 1,3,4-trisubstituted 4,5-dihydro-1H-pyrazoles via 1,3-dipolar cycloaddition has been described. Using this method, various pyrazole were synthesized from eugenol, a major phenolic constituent of clove bud essential oil, as dipolarophilic system and N-aryl-C-ethoxycarbonitrilimine: the (Z)-ethyl 2-bromo-2-(2-(4-chlorophenyl)-hydrazono)acetate.
