The main purpose of this study is to determine Information and Communication Technology and persons with special needs in Calabar Municipality in Cross River State, Nigeria. To achieve the purpose of this study, three hypotheses were formulated. Survey research design was adopted for the study. A sample of one hundred and fifty persons with disabilities was randomly selected for the study. The selection was done through the simple random sampling technique. This was to give equal and independent opportunity to all the respondents to be selected for the study. The questionnaire was the major instrument used for data collection. The instrument was subjected to both face and content validation by expert in measurement and evaluation. The reliability estimate of the instrument was established through the test-retest reliability method Pearson product correlation analysis and independent t-test were employed were adopted to test the hypotheses at .05 level of significance. The result of the analysis reveals that Information and Communication Technology (ICT) significantly relate with persons with hearing and hearing impairments. The result also revealed that there is a significant difference between male and female persons with learning disabled on their perception of information and communication technology (ICT).