This paper describes Two-word and Three-word Disambiguation Rules for Telugu language sentences, which are written in WX-notation. Generally in real life good number of words, which are having many meanings. If a word has many meanings, then we can call it as a word ambiguity. To resolve a word ambiguity, Natural Language Processing (NLP) system having lot of Word Sense Disambiguation (WSD) [1] methods. Among many methods, here we are proposing rule based method for Word Sense Disambiguation.