4 -acetyl -3-(4-substitutedphenylamino)- isoxazole - 5(2H)-one, substituted on nitrogen with a 2-chlorobenzo[d] oxazole group, reacts with triethylamine (TEA) in ethanol under reflux conditions to provide a convenient synthesis of 1-(2-(4-substitutedphenylamino)-imidazo-[2,1-b]-benzoxazol- 3-yl)-ethanone.