Aims and Objectives: Mutations in BRCA1 gene are associated with greater risk of developing breast cancer. We determined whether clinicopathological characteristics of the tumour differ in patients with and without BRCA 1 expression. Materials and Methods: The study was conducted in 100 cases of breast carcinomas received as lumpectomy or mastectomy specimens in the Department of Pathology, Sri Guru Ram Das Institute of Medical Sciences, Amritsar over a period of one year(between November 2013 and October 2014).