Uric acid, the prime end product of purine catabolism, has been implicated in diabetes mellitus as well as in hyperlipidemias. Its significance in diabetic hypercholesterolemia is not established. A study was under taken to assess the relationship of plasma cholesterol with plasma uric acid in type-2 diabetes mellitus subjects. A fasting blood sample was collected from normal as well as type-2 diabetic subjects, the separated plasma was employed for the estimation of glucose, cholesterol and uric acid levels. It is observed that there is a proportional rise in uric acid in type-2 diabetic subjects, suggesting that plasma uric acid levels along with total cholesterol levels aids to asses the diabetes induced dyslipidemia as well as to control the diabetic dyslipidemia induced complications in type-2 diabetes mellitus.