The present research work is intended to optimize the machining parameters for achieving high dimensional accuracy in wire electric discharge machining (WEDM). Experiments were designed and carried out to evaluate the best parametric setting which gives parameters like power, spark gap and corner radius using Inconel X-750 as workpiece material. These parameters are determined for a wide range of job thickness and mathematical correlations were developed for the parameters such as power and spark gap. Analysis of variance (ANOVA) is also performed to study the fitness. This procedure eliminates the need for repeated experiments which saves time and material unlike conventional machining process. The primary objective of the study is to find out the important and combination of one or more factors that influence the machining process in order to achieve the best power setting in turn machining current. Also, Machinability index of various materials which can be machined by WEDM is evaluated by referring to the present research work and literature review.