Background: Inflammatory breast cancer (IBC) is a clinical condition characterized by varied incidence, geographical distribution, and poor prognosis. We conducted this study to trace his epidemiological and immunihistochemical, evolution. Methods: Case files were collected from the archives of the National Institute of Oncology. Inclusion criteria included: − Aproven histological diagnosis of breast cancer − Skin erythema over at least one third of breast − Symptoms appearing over a period of under six months Results: We collected 172 cases, incidence was 5%.Erythema in more than one third of the breast, orange peel skin and edema was present in all patients.126 patients had a localized disease ,46 patients were metastatic.