Introduction: Mucocele of the appendix is a rare lesion which denotes a distension of the lumen due to accumulation of mucoid substance. Material and Methods: This study aimed to evaluate short-term outcomes of single incision laparoscopic ileocecal resection forlow-grade appendiceal mucinous neoplasm (LAMN).This study represents a single-center, retrospective, observational case series analysis. Between January 2011 and July 2015, 9 patients with preoperative appendiceal mucinous neoplasm underwent SILS at our institution. Results: In this retrospective study, the data of 9 consecutive patients with a mean age of 70 years were analyzed. Pathological findings is 6 LAMN, 1 appendiceal cancer, and 2 appendicitis. The median operative time was 152 minutes, and the median blood loss was little. No conversions to open surgery or intraoperative complications occurred. Postoperative complication is 1 anastomosis of leakage. In conclusion, it is thought that minimally invasive procedures, including single incision laparoscopic ileocecal resection, for LAMN.