Despite the scarcity of autopsy case reports in the 19th century 3 of them are abridged in order to demonstrate that none was recognized as a primary lung cancer despite the striking presence of tumor in the lung. This is explicable on the basis of the striking phenomenon of selectivity of one or both adrenal glands during colonization. Therefore, it is concluded that recognizing such peculiar cases of adrenal selectivity among present-day patients will facilitate the treatment of this fell disease. In fact, recent positive papers on both surgery and radiotherapy are illustrative of this hopeful outlook.