In this study we have investigated the impact of Cell Phone on Pakistani Culture with special reference to Multan Region. We constructed a questionnaire and conducted a field survey and collected data through face-to-face interviews of 206 respondents, who were randomly selected. Our purpose of Research was to measure the cultural changes in Pakistan due to the use of cell phone and its impact on Pakistani society particularly youth. We used demographic statistics, Likert scale and Multiple Regression methods as measurement scales. The results of our study are robust and significant because we found that the use of cellphone has brought significant change in Pakistani culture, norms, habits and behavior of the people. However, some changes are positive and some are negative. We specifically noted that cheap night packages of cellphone and internet companies is bringing negative effect on the study of students and their other physical activities.