Introduction: Surgical excision and antifungal chemotherapy are definitive treatment of eumycetoma. To show wide surgical excision plus reconstruction as a surgical modality for big size eumycetoma. Methods: This is prospective, centred based study. Patients who underwent wide surgical excision and reconstructions after surgery were selected. We checked different variables age, sex, site of eumycetoma, the size of eumycetoma lesion, history of recurrence and types of reconstruction done. Results: Wide surgical excision was done for 24 patients. Patients characteristics revealed male: female ratio is 5:1. History of recurrence occurred in 11 patients. Diagnosis of eumycetoma confirmed cytologically. Bone x-ray revealed no involvements. Eumycetoma was found in a variable site. In this study site of eumycetoma were Knee 6 patients, foot 6 patients, leg 4 patients, hand 4, gluteal 3 and hand in 1 patient. The size of eumycetoma lesions were variables from 8 to 20 cm diameters. All patients receive antifungal therapy. Types of reconstruction done for those patients varied from local to advance flaps and or skin grafts. Conclusions: Reconstruction after wide excision gives good outcome in big size eumycetoma lesions with combination therapy of medical treatments.