F: Diseases (101)
GJMR: F
Estimation of New Drug Product Approval Probabilities in Phased Clinical Trials
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 5
This paper proposes and presents a method for the estimation of approval probabilities of new drug or product. The proposed method assumes that three evaluation communities are used to assess and evaluate the quality of a new drug or product and that the evaluation is done by the committees in three period phased clinical trials of the drug product using matched samples of subjects at ea...
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Authors Okeh UM, Oyeka ICARead Journal Click Here
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Page No. 5 to 16
Helicobacter Pylori and Steps for its Elimination: A Review
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 4
The only host for H. pylori is human and it is found to be present in stomach, duodenum, oesophagus and rectum. H. pylorus is responsible for causing chronic infections and therefore its complete eradication from the society is very much essential. This article therefore aims to review the recent treatment options prevalent for the eradication of this dreadful disease. ...
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Authors Manash Pratim SarmaRead Journal Click Here
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Page No. 31 to 36
Medico Social Study of Aged Persons: A Case Study from Serampore City
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 4
Ageing is a biological process, experienced by mankind. Ageing is a dynamic process, determined by the relative size of the younger and older. However, concern for Ageing of population is a relatively new phenomenon, which has raised due to significantly large increase in the number and proportion of aged persons in the society. The phenomenon of population Ageing is becoming a major con...
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Authors Partha TalukdarRead Journal Click Here
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Page No. 23 to 30
Testosterone and Vitamin D Deficiency as Risk Factors for Hip Fracture Elderly Male Patients: Time for Vitamin D and Testosterone Replacement
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 4
Twenty eight male patients with non-pathological fracture neck of femur (FNOF), age range 61-89 years, mean age 74.4 years, presented for surgery for fracture neck of femur to Merlin Park Regional Hospital, Galway Ireland and 28 age and sex matched control patients, age range 60-85 years, mean age 72.4 years who were admitted to the medical ward for chest pain were included in the study....
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Authors Awad Magbri MD, Gussail MA, Eussera El-Magbri, Smew MA, Mariam El-Magbri, Taha El-Magbri, H. Grimes, J KellyRead Journal Click Here
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Page No. 15 to 18
The Prevalence and Risk Factors of Cardiovascular Comorbidity in Patients with Severe and Very Severe COPD
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 4
Cardiovascular comorbidities are most frequent comorbidities in COPD and are responsible for many deaths in those patients. The aim of the study was to investigate the prevalence and the risk factors of these comorbidities. In the survey 114COPD patients were included with severe and very severe stage of the disease, FEV1<50%, which were stable. Cardiovascular comorbidity was detected in...
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Authors Jagoda Stojkovikj, Beti Ivanovska-Zafirovska, Irina Angelovska, Angela Debreslioska, Sead Zejnel, Smiljko Jovanovski, Dragana Stojkovikj, Sasha Anastasova, Ivana JovanovskaRead Journal Click Here
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Page No. 7 to 13
Prevalence of Helicobacter Pylori Infection among the Whole Spectrum of Age and the Performance of the Different Diagnostic Tests
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 4
Design, setting, participants & measurements: Three hundred and thirty eight patients were included in the study. They presented to the endoscopy suite at University College Hospital Galway, Ireland (UCHG) with upper gastrointestinal symptoms. The age range is 21-90 years with a median age of 52 years, 62% females, and 24% diabetics. They were divided into 3 groups 18-30 years, 31-60 yea...
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Authors Awad Magbri, Eussera El-Magbri, Mariam El-Magbri, Fiona StevensRead Journal Click Here
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Page No. 1 to 5
Duodenal Brush Border Enzymes in Helicobacter Pylori Infection
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 3
Background and Objectives: H. pylori are an accepted cause of chronic active gastritis and commonly associated with both gastric and duodenal ulcer. Moderate to severe gastritis increases the relative risk of developing peptic ulceration and eradication of the bacteria reduces duodenal ulcer recurrence. The effect of H pylori on the duodenal brush border membrane enzymes have not been st...
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Authors Awad Magbri, Fiona StevensRead Journal Click Here
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Page No. 33 to 35
Knowledge, Attitude and Practices towards Noncommunicable Disease Risk Factors among Medical Staff
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 3
Background: The Iraq suffers from a high burden of noncommunicable diseases (NCD). Iraqi people have a high prevalence of child obesity, adolescent and adult obesity, diabetes, heart disease and cancers among its adult population. Objective: To identify knowledge, attitude and practices relating to modifiable noncommunicable disease (NCD) risk factors regarding medical staff that include...
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Authors Dr. Suadadj.AL-DaboonyRead Journal Click Here
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Page No. 5 to 19
The Prevalence of Hearing Loss in Chronic Kidney Disease Bangladeshi Patients Undergoing Dialysis
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 4
Objectives: End stage renal failure patients, face multiple complications. One of them is the involvement of auditory system. The aim of this study was to determine the prevalence and degree of hearing loss in CKD patients on haemodialysis. Methods and Results: This cross sectional study was conducted from July 2014 to June2015.The subjects consist of 50 CKD patients on haemodialysis. Th...
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Authors Rezwanur Rahman, Nayareen AkhtarRead Journal Click Here
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Page No. 19 to 22
Oncolytic Activity of Bacteria used in Cancerous Disease Gene Therapy
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 3
Gene therapy is a therapeutic strategy based on using genes as pharmaceuticals. Gene therapy holds promise for treating a wide range of diseases, including cancer, cystic fibrosis, heart disease, diabetes, hemophilia and AIDS. Various types of genetic material are used in gene therapy; double-strained DNA (dsDNA), single strained DNA (ssDNA), plasmid DNA and antisense oligodeoxynucleotid...
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Authors Valencakova, A ,Dziakova, A., Hatalova, E.Read Journal Click Here
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Page No. 27 to 31
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Systemic and Local Immune Response to H. Pylori Infection and their Correlation with the Degree of Antral and Duodenal Inflammation
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 3
Design, setting, participants & measurements: One hundred and eight patients presented to the University College Hospital Galway, Ireland (UCHG) with upper gastro-intestinal symptoms were included in the study. There were 52 males with age range 18-82 years, mean age 49 years, and 56 females, age range 20-83 years, mean age 52 years. They were grouped according to the endoscopic findings...
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Authors Awad Magbri, Fiona StevensRead Journal Click Here
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Page No. 21 to 26
The Sensitivity and Specificity of Clinical Examination of the Hemodialysis Arterial-Venous Fistula (AVF) as Compared to Angiography
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 3
Background and Objectives: Physical examination of the hemodialysis arterial-venous fistula (AVF) is convenient and inexpensive, and can often detect common problems associated with hemodialysis access. Routine systematic physical examination of the fistula by the dialysis staff with each treatment may allow early detection of problems that are commonly associated with mature fistula. Th...
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Authors Awad Magbri, MD, Ji-Yank Sophie Lee, MD, Eussera El-Magbri, Mariam El-Magbri, Taha El-MagbriRead Journal Click Here
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Page No. 1 to 4
Comparison of Binary Models for the Associated Factors Affecting Recovery Status of Vesicovaginal Obstetrics Fistula Patients: A Case of Mettu Hamlin Fistula Center, South West Ethiopian
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 3
Back ground: Obstetric fistula or vaginal fistula is a medical condition in which a fistula (hole) develops between either the rectum and vagina or between the bladder and vagina after severe or failed childbirth, when adequate medical care is not available. It is the most tragic of preventable childbirth complications in the developing world, as affected women are often abandoned by the...
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Authors Aboma TemesgenRead Journal Click Here
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Page No. 37 to 44
Adrenal Selectivity in Lung Cancer Metastases: Historical Highlights and Present Prospects
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 2
Despite the scarcity of autopsy case reports in the 19th century 3 of them are abridged in order to demonstrate that none was recognized as a primary lung cancer despite the striking presence of tumor in the lung. This is explicable on the basis of the striking phenomenon of selectivity of one or both adrenal glands during colonization. Therefore, it is concluded that recognizing such pe...
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Authors Wilson OnuigboRead Journal Click Here
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Page No. 15 to 16