Introduction: In preliminary studies, we have determined that there is a high adhesion and usefulnesswith the use of virtual spaces (TLVE) in Anatomy students as a teaching resource which is supplemental to practical assignments (PA) of the subject. The population on which studies have been conducted showed an important heterogeneity regarding the social-economic characteristics of participants.Purpose: To assess the impact of the social-economic factor of students in the parameters of use, adhesion and performance in the virtual space, with specification of the teaching techniques used. Materials and Methods: Observational, retrospective and transversal study on parameters of use and performance with a TLVE in a cohort of 309 students. Results have been divided by areas of the subject, statistical parameters have been applied (descriptive and inferential)and they were correlated with the above- referenced data of social-economic characteristics. The work complies with applicable ethical-legal regulations. Results: The working hours of students were correlated with the use of the TLVE (number of inclusions/dayr2=0.75and weekr2=0.78)and performance in clinical-surgical cases was proportional to the loggingtime(r2=0.75). Conclusions: Working activity together with university studies and, specially, the time of weekly working activity, were determining factors in the performance obtained in the virtual space and in the parameters of use of the technological resource. Key terms: Anatomy. Teaching. Social-economic factor. Teaching and learning virtual space.