Wireless transmission is affected by fading and interference effects which can be combated with equalizer. The use of MIMO system promises good improvement in terms of spectral efficiency, link reliability and Signal to Noise Ratio (SNR). The effect of fading and interference always causes an issue for signal recovery in wireless communication. Equalization compensates for Inter-Symbol Interference (ISI) created by multipath within time dispersive channels. This paper analyzes the performance of Zero forcing method for MIMO wireless channels. The simulation results are obtained using MATLAB. The Bit Error Rate (BER) characteristics for the various transmitting and receiving antenna simulates in MATLAB and describes many advantages and disadvantages of the system. The simulation results show that the equalizer based zero forcing receivers is good for noise free channel and is successful in removing ISI.