Critical Success Factors was the key to success for the Clothing and Textile industry in the Export Processing Zones (EPZ) in Mauritius in 1971. Many articles have demonstrated that it was mainly due to conducive environment for investment, exogenous factors and preferential trade arrangements. However, with changing business environment, these factors have evolved with great importance in order to keep the industry competitive. A mixed method methodology was used using quantitative and qualitative methods. The findings shows the evolution of the Critical Success Factors in the order of importance with Cost effectiveness and Human and physical resources preceding Supportive environment and Capital investment after more than 40 years of existence.