Since the early times, medicinal plants have been used in healing and preventing diseases. The chronic use of substance(s) can cause some irreversible physical and psychological development1. The use of substance could be beneficial or harmful depending on how it is been used. Substance(s) could bring about a change in the biological function of living organism through its chemical composition4. It can also modify perception, cognition, mood, behaviour, and general body function9. They could thus be considered as chemical modifiers of the living tissues that could bring about psychological and behavioural changes11. The use and abuse of substance(s) by youths have become one of the most disturbing health related phenomena in society; several youths have become insane, irresponsible and liability to the society. Substance(s) can be used for treatment or prevention of disease in man or animals; it also alters the body function, either positively or negatively, depending on the body composition of the user, type of substance(s) used, dose used, or combination with other substance(s) at the same time3. NAFDAC explains the term substance abuse as the excessive and persistent usage of a substance without regard to the medically or culturally accepted patterns.