B: Pharma, Drug Discovery, Toxicology & Medicine (132)
GJMR: B
NT-proBNP as a Diagnostic Marker in CCF
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 4 • Heart failure prevalence is raising throughout the world. • The overall prevalence of HF is thought to be increasing because current therapies for cardiac disorders, such as Myocardial Infarction (MI), Valvular Heart Disease, and Arrhythmias, are allowing patients to survive longer. • American Heart Association (AHA) guidelines define HF as a ...
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Authors Dr. Hitesh M R,Dr. Vedavathi R.Read Journal Click Here
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Page No. 51 to 56
Antihypertensive and Antiatherogenic Effects of Tanopati a Traditional Recipe used for the Treatment of High Blood Pressure
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 4 Background: The objective of the present study was to investigate the possible effect of Tanopati on induced hypercholesterolemia in rats and hypertension in rabbits. Methods: Twenty wistar rats were divided into 4 groups each and then subjected to different treatments. Hypercholesterolemia was induced by induced dietary cholesterol; the rats are then treated with Tanopati and QuestranÃ...
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Authors Amani Komenan Nazaire, Djyh Bernard Nazaire, Boga Gogo Lucien, Kouassi Konan, Severin Kouakou Konan, Nu00e2u20acu2122Guessan Jean DavidRead Journal Click Here
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Page No. 43 to 49
Synergic Anticancer Activity of Different Extracts of Ziziphusa Mauritiana and Punica Grantum L on the Inhibition of Hela Cell Proliferation and Tumor Growth in EAC Bearing Mice
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 4 In consideration of the synthetic chemicals chemotherapy has induced obnoxious hazards, there is a ubiquitous tend towards the natural resources, which are remedially potent and affordable for the poor people. Development of phenolic compounds or extracts has become a major area medical research due to their cancer preventive effects through induction apoptosis and prevention of oxidativ...
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Authors Somayeh Afsah Vakili, Arash ParviziRead Journal Click Here
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Page No. 1 to 14
Assessment of Substance Abuse among Students of College of Health Sciences and Technology Ijero Ekiti.
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 4 Since the early times, medicinal plants have been used in healing and preventing diseases. The chronic use of substance(s) can cause some irreversible physical and psychological development1. The use of substance could be beneficial or harmful depending on how it is been used. Substance(s) could bring about a change in the biological function of living organism through its chemical compo...
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Authors Boluwaji Akinsefunmi, Ogboh Rita, Hassan Aminat, Babalola Rufus.Read Journal Click Here
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Page No. 15 to 42
Prevalence of Health Related Disability among Community Dwelling Urban Elderly from Middle Socio-Economic Strata in Serampore
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 3 The present study has been conducted in Serampore, West Bengal. The health of geriatric population is a present as well as future concern. This poses mounting pressures on various socio-economic fronts of the state, including pension outlays, health care expenditures, saving levels etc. This makes it necessary to look into the various aspects of their problems: Health, social rejection, ...
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Authors Partha TalukdarRead Journal Click Here
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Page No. 25 to 31
Endocrine Disruptors in Endometriosis
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 3 Endometriosis is an estrogen-dependent disease, which involves the growth of endometrial tissue outside the uterine cavity, commonly in the pelvic region. The etiology of the disease is unclear, but multiple factors may contribute to its prognosis. Toxicological studies indicate that many chemicals are able to interfere with endocrine homeostasis, called endocrine disrupting chemicals (E...
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Authors Mariana Antunes Ribeiro, Wellerson Rodrigo ScaranoRead Journal Click Here
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Page No. 21 to 24
The Relation of Serum High-Sensitive C- Reactive Protein to Serum Lipid Profile, Vitamin D and Other Variables in a Group of Hypertensive Patients in Erbil-Iraq
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 3 Background and objectives: Hypertension is an established risk factor for atherosclerosis. Elevated levels of high-sensitive C-reactive protein (hs-CRP) were detected in hypertensive patients. Recent studies suggest a link between high-sensitive C-reactive protein (hs-CRP) and atherosclerosis in hypertension. Growing evidence suggests that vitamin D affects the cardiovascular system The ...
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Authors Salam Naser ZanganaRead Journal Click Here
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Page No. 15 to 20
Copper (II) Oxide Nanoparticles Induce High Toxicity in Human Neuronal Cell
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 3 Copper (II) oxide nanoparticles (CuO-NPs) are widely used in industry, cosmetics and medicine. People have increasingly been exposed to these active materials. Several studies indicate that CuO-NPs could be taken up by different organs and cause toxicities. However, there is still a lack of data on the toxicological effects of CuO-NPs in neuronal system. In the present study, the toxic p...
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Authors Abudayyak Mahmoud, Guzel E. Elif, Ozhan Gu00c3u00bclRead Journal Click Here
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Page No. 7 to 14
Assessment of Volume Status of Hemodialysis Patients using Sonographic Lung Comets
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 3 Background: Fluid balance is important in patients with renal impairment and undergoing hemodialysis. ‘‘Dry’’ weight is usually assessed clinically, and also, bioimpedance is considered reliable. The use of chest ultrasound to detect lung water received growing attention in clinical research in intensive care patients and in p...
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Authors Hala S El-Wakil, Iman E El-Gohary, Doaa M. Emara, Reham Abd El WahabRead Journal Click Here
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Page No. 1 to 6
Miscarriage and Oxidative Stress of Iron Supplementation during Pregnancy
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 2 Background: Iron supplementations to the pregnant women in Iraq mostly considered as obligatory routine health care additive treatment without real assessing to the iron status in these people, therefore the acceptable range of iron must be estimated and the relationship between iron status and miscarriage should be explored. Objective: In miscarriage and pregnant women that supplemented...
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Authors Ahmed M. IssaRead Journal Click Here
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Page No. 9 to 17
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The Pharmacological Mechanisms of Anthocyanin in Aqueous Extract of Purple Sweet Potato as Antihyperglycemic Herbal Remedy
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 2 Aims/hypothesis: The aqueous extracts of purple sweet potatoes contained highly anthocyanin and has a hypoglycemic effect and prevent oxidative stress. The pharmacological mechanisms of this anthocyanin is not clear. The antioxidant effect of anthocyanin is proposed could protect the oxidative stress of pancreatic β-cell and recovery their function. Methods: The fifteen Wistar-rat...
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Authors I Made Jawi, I Gusti Kamasan Nyoman Arijana, AAN Subawa, I Made Agus Gelgel WirasutaRead Journal Click Here
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Page No. 27 to 32
Mass Spectrometric Identification of Catabolic Pathways in the Selected Amphibian Skin Peptides With the Saliva and the Major Salivary Protease, Kallikrein
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 2 As nature has selected amphibian skin defensive peptides for inter-species delivery through the oral route in the recipient, structural stabilisation modifications may have occurred to facilitate this and such information would be most useful and could potentially provide new insights to the design of orally-active and selectively-targeted peptide therapeutics. The purposes of this study...
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Authors Xiaole Chen, He Wang, Lei Wang, Mei Zhou, Tianbao Chen, Chris ShawRead Journal Click Here
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Page No. 1 to 7
Antioxidant Activity of Phenyl Alanine Mandelates by Chemical and Electrochemical Methods
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 1 Food decomposition in human body due to the redox reactions results in the formation of reactive oxygen species (ROS). ROS obtained during metabolic activitities in our body are responsible for cancerous diseases. ROS are scavenged by hydroxyl radicals present in the small organic molecules. Novel small organic molecules like mandelic acid - amino acid complexes, possess the weak hydroge...
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Authors Usha S, Charles Kanakam ChristopherRead Journal Click Here
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Page No. 1 to 6
Trade in Non-Mammalian Wild Animals for Traditional African Medicine in Ogun State, Nigeria
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 1 A steady rise in the patronage for Traditional African Medicine (TAM) has necessitated a corresponding increase in the demand for the ingredients used in the preparation of the trado-medicines. These ingredients are the various wild animals and plants parts. The attendant rise in this demand for ingredients calls for a need to document the extent of utilisation of these natural resources...
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Authors Durojaye A Soewu, Gabriel A Dedeke, Victor A Ojo, Opeyemi K SoewuRead Journal Click Here
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Page No. 7 to 16