B: Pharma, Drug Discovery, Toxicology & Medicine (132)
GJMR: B
Design, Synthesis, Spectral Charecterization of Some New Fully Unsaturated 2-Substituted-4, 6 DichloroSymmetric Triazine- Based Chalcone Hybrids
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 1
Triazines and chalcones are interesting class of heterocyclic compounds with a prominent structural core system present in numerous pharmacologically active compounds. It is proved from the literature that the compounds containing 1,3,5-triazine moiety or chalcone bridge often shows significant biological activity profiles. Based on these observations, it was considered worthwhile to syn...
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Authors G. V. Pavan Kumar, D. Srinivasa Rao, B. Pooja, G. Harika, Y. Anil KumarRead Journal Click Here
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Page No. 17 to 29
Ethnopharmacological Surveys’ Methodologies for Medicinal Plants uses Discovery and Environmental Threatens on Recorded Plants from Indigenous Knowledge in Cameroon.
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 5
Nowadays, more than 80% of the world population is depending on medicinal plants based medicines to satisfy their healthcare needs. Medicinal plants have served as valuable starting materials for drug development. The general objective of the present work was to exploit the strong experience, developed since the antiquity on medicinal plants uses in Cameroon, for their future valorizatio...
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Authors Nole Tsabang, Lionel Wilfried Djeufack Tsambang, Armel Tedjou Nouboudem, Denis Sonwa, Alain Bertrand Dongmo, Aloys Bernard NkongmeneckRead Journal Click Here
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Page No. 19 to 27
Elecrochemical Study of the Capacity of Moringa Oleifera to Chelate p-Aminophenol
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 5
We report a sensitive electrochemical voltammetric method for analyzing p- Aminophenol, using a Natural phosphate (NP) modified carbon paste electrode NP-CPE, in Na2SO4, solution. Operational parameters have been optimized, and the stripping voltammetric performance has been studied using square wave voltammetry. The use of Moringa oleifera as natural chelating agent gave a significant i...
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Authors A. Zaroual, S. El Qouatli, A. Bellochou, M. Boulghallat, A. Gamouh, R. Najih, A. ChtainiRead Journal Click Here
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Page No. 9 to 18
Preliminary Phytochemical Investigations with Quantitative Fractionation of Orange Pulp (Citrus Aurantium Var. Dulcis L.): Natural Product Waste as Medicine
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 5
Day by day, faith of people on herbal medicine increases due to the side effect of synthetic drugs; this has resulted into people falling back to the traditional knowledge of plant for their health care. Certain local practitioner and traditional healers use the fruits of Citrus aurantium var. Dulcis L pulps in various disease management and so, they advise to eat the pulps along with th...
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Authors Rufai Y., Fatimah S.Read Journal Click Here
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Page No. 1 to 7
Assay for Quantitative Analysis of Losartan Potassium by using UV Spectroscopy
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 4
Drug is a substance that brings about a change in the biological functions through its chemical actions. Drug losartan are the first marketed beta blockers of the angiotensin II-type (AT1) receptor. It is the prototypic ARB. Their pharmacologic effect are very similar to the ACE inhibitors, because they also produce the arteriolar and venous dilation and block aldosteron secretion, thus ...
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Authors Zehra Ashraf, Nimra Waheed, Erum Naz, Fatima Ahmed, TaibaAsim, Fatima Muzammil, Syeda Saghira and Maria AyubRead Journal Click Here
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Page No. 35 to 37
Prescription Pattern of Injection at Out Patient Pharmacy Department of Adama Hospital Medical College, Adama, Ethiopia
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 4
Introduction: Injection is an infusion method of putting drugs or fluids in to the body with a hollow needle and a syringe. The use of injection for treatment accompanied with variety of disadvantages including sepsis at administration, risk of tissue toxicity, costly difficulties in correcting the error. Injections are very expensive compared to other dosage forms and require trained pe...
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Authors Belayneh Kefale Gelaw, Adunya Feyissa, Gobezie Temasgen Tegegne, Amsalu Degu Defersha, Getasew Amogne AyinalemRead Journal Click Here
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Page No. 27 to 33
Drug Therapy Problem and Contributing Factors among Ambulatory Hypertensive Patients in Ambo General Hospital, West Shoa, Ethiopia
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 4
Background: Hypertension is the most serious health problems in the world. Though modern medicine can improve the well-being, its benefit can be compromised by drugrelated problems (DTPs). Objective: The objective of the study is to determine both type and number of drug related problems and factors affecting it in Ambo General Hospital. Methods: A hospital based cross –...
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Authors Gobezie Temesgen Tegegne, Tezere Gaddisa, Belayneh Kefale, Gurumu Tesfaye, Jimma Likisa, Minyahil Albachew, Hunduma Dinsa, Amsalu Degu DefershaRead Journal Click Here
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Page No. 21 to 25
Characterization of Extract of P.Notatumisolated from Virgin Forest
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 4
Penicillium notatum has been found years ago to be one of the leading novel candidates of fungi for the discovery of novel antibiotics. The fungus was isolated from eighty years old virgin forest Ikota, Ondo state. The fraction was obtained through column chromatography using mixture of solvents, after culturing and purification process of the extract. The fraction was characterized usin...
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Authors Adewole Ezekiel, Idris O. O., Olajuyigbe A.BRead Journal Click Here
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Page No. 5 to 20
Emergence of Allium Cepa as Antitubercular Agent
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 4
Tuberculosis (TB) is the main cause of morbidity in modern era and a latent infection affecting nearly one third of world’s population including forty percent from India. There is an urgent need to explore the effective and promising new anti– tubercular drugs to combat against Tuberculosis. Nature provides diverse secondary metabolites with anti- tuberc...
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Authors Shashidhar Mehta, Sandhya S Mehta, Pankaj Patyal, Suhasini BhatnagarRead Journal Click Here
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Page No. 1 to 3
Drug-induced Disparities in Cell Restoration and Debridement: Ethanol-Triggered Nuclear Misreading of the Restitution Cues
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 3
The consequences of the drug-triggered cues from nucleus to cytosol in the restoration of intracellular organelles, cell structure, and function were investigated. The synthesis of the ER-assembled transporters in the cytosol, primed by incubation with nuclei in the presence of ethanol, was manifested by a 26% decrease in the assembly of cell organelle-restoring vesicles, 30% decline in ...
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Authors Amalia Slomiany, Bronislaw L. SlomianyRead Journal Click Here
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Page No. 23 to 38
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Drug Related Problems that Occurredin Patient Sepsis Macrovascular Disease Complications General Hospital Treatment Room Central of the Army (Army Hospital) Gatot Subroto
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 3
Sepsis is a systemic inflammatory response syndrome: clinical inflammatory response to disturbances that cause infection or not infection1. Patient entered in the Emergency Room (ER) 8 October 2014, the diagnosis of sepsis patient ec furnier gangrene (scrotum), Haematemesis ec gastropathy uremikum, CKD stage V on HD with anemia, metabolic acidosis, CHF fc II, type II diabetes mellitus, h...
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Authors Abdullah, Diana Laila Ramatillah, Aprilita Rinayanti EffRead Journal Click Here
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Page No. 11 to 14
Rhodiola rosea from the Selection of Traditional Applications to the Novel Phytotherapy for the Prevention and Treatment of Serious Diseases.
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 3
Rhodiola rosea is a remarkable herbthat has been a part of traditional medicine systems in order to stimulatethe nervous system, toprotect thebody against oxidative stress, free radical damage, inflammation, and virus infection. Rhodiola rosea is included among a class ofplant derivatives called adaptogen,an agent thathelps the body adapt to various stressors. Adaptogens have been claime...
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Authors Dr. Rafie Hamidpour,Dr. Soheila Hamidpour, Dr. Mohsen Hamidpour, Mrs. Mina Shahlari,Mrs. Mina Shahlari, Mrs. Mahnaz Sohraby, Ms. Nooshin Shahlari,Ms. Roxanna HamidpourRead Journal Click Here
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Page No. 1 to 10
Chemistry, Pharmacology and Medicinal Property of Frankincense(Boswellia Species): From the Selection of Traditional Applications to theNovel Phytotherapy for the Prevention and Treatment of Serious Diseases.
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 3
Frankincense, the resinous extract from the trees of the genus Boswellia, has been used for centuries in ceremonial, cosmetic, cultural and as a traditional medicine to treat a variety of ailments especially inflammatory diseases including asthma, arthritis, cerebral edema, chronic pain syndrome, chronic bowel diseases, cancer and some other illnesses. Boswellic acids are the active comp...
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Authors Rafie Hamidpour, Soheila Hamidpour,Mohsen Hamidpour, Mina Shahlari, Roxanna Hamidpour4Read Journal Click Here
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Page No. 15 to 22
Formulation & Evaluation of Eye Care Solution of Vasoconstrictor and Antihistaminic Drug for Conjuctivitis
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 15 Issue: 2
The purpose of present research work was to formulate and evaluate eye care solution of Naphazoline hydrochloride (Vasoconstrictor) and Pheniramine maleate (Antihistaminic) drug for allergic conjunctivitis. The optimum values of responses for viscous eye care solution formulation was found to be 97.6 cps viscosity, 1759 cps mucoadhesion index and 96.67 % CDR for naphazoline hydrochloride...
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Authors Mehul B. Vyas, Dhaval Patel, Dr. Samir K.ShahRead Journal Click Here
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Page No. 19 to 34
