Global Journal of Medical Research (900)
GJMR
Children categories
Estimation of New Drug Product Approval Probabilities in Phased Clinical Trials
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 5
This paper proposes and presents a method for the estimation of approval probabilities of new drug or product. The proposed method assumes that three evaluation communities are used to assess and evaluate the quality of a new drug or product and that the evaluation is done by the committees in three period phased clinical trials of the drug product using matched samples of subjects at ea...
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Authors Okeh UM, Oyeka ICARead Journal Click Here
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Page No. 5 to 16
Pilot Study Revealed Association of DRD4 Promoter Variants with ADHD Associated Functional Deficit in Indian Probands
Published In: GJMR Part: A: Neurology & Nervous System Volume: 16 Issue: 2
Background: Attention Deficit Hyperactivity Disorder (ADHD) is often associated with cognitive deficit. Since brain regions regulating cognition has higher expression of Dopamine receptor 4 (DRD4), we explored association between functional DRD4 promoter variants and cognition of ADHD probands. Methods: Subjects recruited following DSM-IV-TR were assessed for Short Attention Span (SAS) a...
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Authors Subhamita Maitra, Kaushik Mukherjee, Mahasweta Chatterjee, Arijit Karmakar, Swagata Sinha, Kanchan MukhopadhyayRead Journal Click Here
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Page No. 9 to 20
Endocrine Disruptors in Endometriosis
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 3
Endometriosis is an estrogen-dependent disease, which involves the growth of endometrial tissue outside the uterine cavity, commonly in the pelvic region. The etiology of the disease is unclear, but multiple factors may contribute to its prognosis. Toxicological studies indicate that many chemicals are able to interfere with endocrine homeostasis, called endocrine disrupting chemicals (E...
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Authors Mariana Antunes Ribeiro, Wellerson Rodrigo ScaranoRead Journal Click Here
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Page No. 21 to 24
Interaction of Inflammatory Response and Sympathetic Nervous System in the Central Regulation of Chronic Heart Failure in Rats
Published In: GJMR Part: I: Surgeries &Hemolytic anemiascular System Volume: 16 Issue: 4
Objective: To investigate the interaction between immune inflammatory response and sympathetic nervous system in the central regulation of chronic heart failure in rats. Methods: Branch ligation of the left anterior descending the making rat model of chronic heart failure, by AT1 receptor blockade losartan central intervention, intravenous injection of six Ting quaternary amines detected...
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Authors Fang Liu, Wenxiu Zhou, Jinjun LiRead Journal Click Here
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Page No. 1 to 6
The Relation of Serum High-Sensitive C- Reactive Protein to Serum Lipid Profile, Vitamin D and Other Variables in a Group of Hypertensive Patients in Erbil-Iraq
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 3
Background and objectives: Hypertension is an established risk factor for atherosclerosis. Elevated levels of high-sensitive C-reactive protein (hs-CRP) were detected in hypertensive patients. Recent studies suggest a link between high-sensitive C-reactive protein (hs-CRP) and atherosclerosis in hypertension. Growing evidence suggests that vitamin D affects the cardiovascular system The ...
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Authors Salam Naser ZanganaRead Journal Click Here
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Page No. 15 to 20
Intrathoracic Schwannoma: Diagnosis and Surgical Treatment. The Challenge Remains
Published In: GJMR Part: I: Surgeries &Hemolytic anemiascular System Volume: 16 Issue: 4
Schwannoma is a benign neoplasm derived from Schwann cells. It is usually located in intracranial nerves, however intrathoracic presentation is possible, leadings to compression of adjacent structures and symptoms. Its diagnosis is challenging and is achieved by imaging tests. Treatment consists of surgical resection by thoracotomy or thoracoscopy. This study aimed to review the subject,...
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Authors Rielly De Sousa E Silva, Jessica Siebra Macario De Brito, Senival Alves De Oliveira Junior, Thiago Emanuel Veras Lemos, Barbara Monitchelly Fernandes Chaves, Amalia Cinthia Meneses Rego, Irami Araujo-FilhoRead Journal Click Here
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Page No. 7 to 13
Risk Factors Associated with Coronary Artery Disease in Gaza
Published In: GJMR Part: I: Surgeries &Hemolytic anemiascular System Volume: 16 Issue: 4
Aim: Coronary Artery Disease (CAD) is considered the most life threating disease in the world. Our study aims to estimate the association of lipid profile, other risk factors with CAD development. Method: Blood samples were taken from cross-sectional sample (n=94) of CAD inpatients (68 males and 26 females) recorded at the period of 1/6/2008 to 16/8/2008 at El-shefaa hospital of Gaza. Th...
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Authors Samy H. Khwaiter, Abdalla AbedRead Journal Click Here
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Page No. 15 to 22
Comparing Consumption of Green Leafy Vegetables to Cruciferous Vegetables in Relations to Incidence of 17 Different Cancers: A Meta-Analysis
Published In: GJMR Part: L: Nutrition Volume: 16 Issue: 1
Cancer is a group of over 100 different types of malignancies and there are several potential substances in green leafy vegetables (GLV) and cruciferous vegetables (CV) that my exhibit anticancer effects [1]. GLV are leaf vegetables, greens, vegetable greens, leafy greens or salad greens. They come from a very wide variety of plants all over the world, with nearly one thousand species of...
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Authors Richard Lee PollockRead Journal Click Here
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Page No. 39 to 47
Recurring Ischemic Infarcts Showing Biermer’s Disease Associeted with Protein S Deficiency
Published In: GJMR Part: A: Neurology & Nervous System Volume: 16 Issue: 2
Mrs ASS….AKOU, 36 married and right handed household was at her second episode of stroke in six months. Concerning her history; six months ago, during her first episode of stroke she was discovered and known to have a high blood pressure in the left anterior cerebral artery, responsible of an after effects right crural hemiparesis at 4/5. She was not using hormonal contrace...
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Authors Kokou Mensah Guinhouya, Lehleng Agba, Nyinevi Anayo, Mofou BeloRead Journal Click Here
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Page No. 21 to 21
Comparative Evaluation of Upper Airway Dimensions and Oxygen Saturation in Completely Edentulous Patients with and Without Dentures
Published In: GJMR Part: J: Dentistry & Otolaryngology Volume: 16 Issue: 2
Background: Majority of the elderly people complain of difficulty in sleeping. Although the causes for the sleep disturbances may be multifactorial in nature, the sleep disordered breathing (SDB) is one of the primary disorder. The study was undertaken to study the effect of Complete Denture rehabilitation which could have profound impact on rehabilitation protocol on complete edentulous...
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Authors Brig E Mahesh Gowda, Maj Gen NK Sahoo, Lt col Guruprasada, Wg Cdr Naveen KS, Maj Kamal VermaRead Journal Click Here
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Page No. 23 to 28
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Bioavailability and Health Effects of Plastic Contaminants in Borehole Water Stored in Plastic Containers
Published In: GJMR Part: C: Microbiology & Pathology Volume: 16 Issue: 3
The aim of this study was to evaluate the bioavailability and health effects of plastic contaminants on borehole water stored in plastic containers. Three brands of plastic containers filled with borehole water were collected from homes in Ugbowo, Benin city. Physicochemical parameters were determined using standard methods. Total bacterial and coliform counts were determined using the p...
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Authors Adeghe, O.M, Atuanya, E.I, Iyahen, ERead Journal Click Here
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Page No. 1 to 10
Sero-Prevalence of Toxoplasma Gondii Infection and Associated Risk Factors in Animals Presented to Sholla and Akaki-Kality Veterinary Clinics, Addis Ababa
Published In: GJMR Part: G: Veterinary Science & Veterinary Medicine Volume: 16 Issue: 3
A cross-sectional study on Toxoplasma Gondii in livestock was carried from October 2011 to March 2012 in Addis Ababa, Ethiopia to determine sero-prevalence and associated risk factors. A total 347 serum samples were collected from the jugular veins of each animal and heart of swine, presented veterinary clinics and abattoirs, respectively. The overall prevalence in the six animal species...
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Authors Abebaw Getachew, Alebachew Tilahun, Alemu Aylate, Wale TesfayeRead Journal Click Here
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Page No. 11 to 17
Copper (II) Oxide Nanoparticles Induce High Toxicity in Human Neuronal Cell
Published In: GJMR Part: B: Pharma, Drug Discovery, Toxicology & Medicine Volume: 16 Issue: 3
Copper (II) oxide nanoparticles (CuO-NPs) are widely used in industry, cosmetics and medicine. People have increasingly been exposed to these active materials. Several studies indicate that CuO-NPs could be taken up by different organs and cause toxicities. However, there is still a lack of data on the toxicological effects of CuO-NPs in neuronal system. In the present study, the toxic p...
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Authors Abudayyak Mahmoud, Guzel E. Elif, Ozhan Gu00c3u00bclRead Journal Click Here
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Page No. 7 to 14
Helicobacter Pylori and Steps for its Elimination: A Review
Published In: GJMR Part: F: Diseases Volume: 16 Issue: 4
The only host for H. pylori is human and it is found to be present in stomach, duodenum, oesophagus and rectum. H. pylorus is responsible for causing chronic infections and therefore its complete eradication from the society is very much essential. This article therefore aims to review the recent treatment options prevalent for the eradication of this dreadful disease. ...
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Authors Manash Pratim SarmaRead Journal Click Here
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Page No. 31 to 36
